The treatment of cord blood is given either by IV or IT infusion.

Intravenous (IV) - When the blood is given through IV, it goes into the child's bloodstream and encounters his immune system, and therefore it is safer to use.

Intrathecal (IT) - When the blood is given intrathecally, it bypasses the blood-brain barrier (BBB). It is a medical procedure performed under local or general anesthesia, performed in an operating room.

When the given substance (blood) is allogenic, it is highly not recommended to give it through IT.